gPROMS FormulatedProducts is PSE's new platform for the integrated design and optimisation of formulated products and their manufacturing processes.
It allows scientists and engineers to screen formulations for end-user attributes, determine whether they can be manufactured efficiently, and explore the design space of the whole formulation and manufacturing chain.
Formulations on a single platform
Advanced design & optimisation
gPROMS FormulatedProductsTM is an advanced mechanistic process modelling tool, integrating crystallization, solids processing and oral absorption on a single platform. It builds on and strengthens the existing capabilities of gCRYSTAL®, gSOLIDS® and gCOAS® in a systems-based approach that links product performance to process and formulation parameters. Users can screen formulations for end-user attributes, identify risk factors and optimise the entire formulation and manufacturing chain.
Developed with industry partners
Applied science to accelerate innovation
PSE works closely with a number of industrial, research and academic organisations that hold a strong interest in applied engineering and science. This helps our ongoing work in accelerating innovation in model and software development. Some of our recent developments are our updated spray dryers, the conclusion of Systems-based Pharmaceutics (SbP) Phase 1, our collaboration with NIZO and the new ADDoPT project.
Robust & efficient crystallization processes
The gCRYSTAL module provides a mechanistic framework for crystallization modelling. It has a range of models, from crystallizers and wet mills to controllers, instrumentation models and handy comparison tools. Users can confidently design, scale-up, optimise and operate crystallizers and crystallization processes.
Flexible & reliable solids processes
The gSOLIDS module is an advanced process modelling tool for process engineers and scientists. It has a range of integrated steady-state and dynamic models for classification, control, drying, size change, storage and transportation and tableting. Users can easily design flexible and reliable solids processes, scale-up, identify process bottlenecks, reduce the risk of fouling and perform optimisation with multiple decision variables.
A new standard in preclinical simulation
The gCOAS oral absorption module is an analysis tool for prediction of drug absorption in the human intestine as a function of product formulation parameters and ingestion conditions. Developed in cooperation with leading pharmaceutical companies, it provides formulation scientists with a tool to easily and quickly screen new formulations, with the ultimate objective of designing a good dosage form.
Work with our modelling experts
Modelling formulated products and their manufacturing processes can be a challenging task. That is why our consultants are both modelling and domain experts, often specialising in one of our main areas such as crystallization, spray drying, granulation, oral absorption and more. Understanding your problems quickly, we can advise you both on software and model implementation, helping you progress without delay.