Consultant – Physiologically based Pharmacokinetic (PBPK) modelling

Department                Formulated Products

Employment basis      Full-Time, Permanent

Location                      Hammersmith, U.K.

Salary range:              Competitive package


Process Systems Enterprise (PSE) is the leading supplier of Advanced Process Modelling software and digital design and operation technology and services to the process industries.

Passionate, visionary, collaborative and professional; these are some of the things that our customers have said about PSE. From our employees’ perspective, we operate an open, diverse and flexible culture, providing independence, opportunity to innovate, early responsibility and open and respected leadership. Therefore, people tend to stay a long time and grow with the company because at PSE we all have a great working environment that is friendly and supportive, with a real focus on training and development.

We are now looking for a highly motivated product developer to join the Formulated Products and product development teams, focusing on our mechanistic oral absorption, in vitro dissolution and precipitation, and pharmacokinetics model libraries within gPROMS FormulatedProducts.

Your impact:

A Consultant in physiologically based pharmacokinetic (PBPK) modelling in the Formulated Products team uses PSE’s gPROMS Platform and other tools to develop and maintain the mechanistic oral absorption, in vitro dissolution and pharmacokinetics modules within gPROMS FormulatedProducts. He/she works with the technical and commercial colleagues within the team as well as with customers to define requirements and to support taking the product to market.

Your duties and responsibilities will include:

Product development

  • Design, develop and test mathematical models for gPROMS FormulatedProducts
  • Productisation of modules including preparation of documentation, training and demonstration materials
  • Ensure consistency and interoperability with the other modules of gPROMS FormulatedProducts
  • Project execution and delivery to PSE’s customers

Business development

  • Work with clients and prospects to progress product development:
  • Gather requirements, user feedback and enhancement requests
  • Propose formulations for new models based on internal and customer requirements
  • Support existing customers in their application of gPROMS FormulatedProducts
  • Support the sales and marketing efforts of the Formulated Products business
  • Contribute to relevant proposals

Product Marketing

  • Work with Marketing to prepare product marketing material (e.g. brochures, web pages etc.)
  • Give presentations (at PSE-organised or public conferences)
  • Active participation in and contribution to, all aspects of the Company’s technical and commercial activities related to the above.

What skills we are looking for:

  • Ability to understand customer requirements and translate them to commercial software solutions.
  • Excellent oral and written English language skills.
  • Ability to work independently and as a team member.
  • Ability to prioritise scheduled tasks and react to unexpected problems.

What skills you should have:

  • A first degree or PhD in pharmaceutical sciences, computational biology, or chemical engineering. A related technical discipline such as mechanical engineering, physics, biology, biochemistry or chemistry may be acceptable depending on other experience.
  • A minimum of 3 years of modelling experience. Population balance modelling skills or experience with other partial differential equations are of particular interest.
  • An excellent knowledge of biopharmaceutics and hands-on experience developing mechanistic absorption, in vitro dissolution and physiologically-based pharmacokinetic models.
  • Experience with gPROMS®, ACM®, Dymola® or another equation-oriented modelling tool is an advantage.

What we offer you:

  • Flexible working
  • 26 days of holiday per year, plus 8 days of statutory Bank Holidays
  • Company pension
  • Medical insurance
  • Group life assurance
  • Comprehensive internal and external training programme
  • Excellent career development
  • Cycle-to-work scheme
  • Perkbox discount platform
  • Great office environment, with free fruit, coffee and biscuits, and regular social events
  • Reimbursement of professional registration and cost of professional books
  • Internal coaching sessions with a Professional Coach

Application procedure

If you wish to apply, please click on the button 'Apply here' 
Apply here

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