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    14 June 2016

    PSE releases gPROMS ProcessBuilder v1.1 with full dynamics

    First true equation-oriented flowsheeting environment for steady-state and dynamic simulation and optimisation

    We are pleased to announce the full release of gPROMS ProcessBuilder v1.1, the first true equation-oriented flowsheeting environment for steady-state and dynamic simulation and optimisation.

    ProcessBuilder is an integrated environment for steady-state and dynamic modelling of oil & gas, refining, chemicals, petrochemicals, and pharmaceutical processes. It is increasingly being adopted by process industry organisations seeking to deploy a single full-capability modelling tool across the entire process lifecycle in order to reduce cost of ownership while benefiting from 21st century modelling technology.

    A major new feature in v1.1 is a full dynamic simulation and optimisation capability for flowsheets involving key unit operations such as distillation columns. New unit operation models include distributed multi-stream heat exchangers, upgraded shell-and-tube and double-pipe heat exchangers, steady-state and dynamic pipelines, and pressure relief/pressure safety valve models. A set of 'starting point' templates and examples simplify the addition of custom unit operation models, allowing users to capture and deploy knowledge via their own corporate libraries. There are also numerous robustness, usability and speed enhancements.

    ProcessBuilder is used for a wide range of applications from early conceptual design simulation to construction of plant models for online monitoring and real-time optimisation. A key advantage is the ability to perform large-scale optimisation, including mixed continuous and discrete decisions, using high-fidelity models. The recent PSE Advanced Process Modelling Forum in London saw numerous presentations on industrial optimisation applications that identified profit improvements of tens or hundreds of millions of Euros in areas as diverse as multi-site region-wide natural gas processing, refinery crude transition, and site-wide utility systems.

    ProcessBuilder v1.1 takes advantage of many new features of the underlying gPROMS platform, including new numerical solvers and symbolic model reduction techniques that improve robustness and significantly accelerate performance of dynamic flowsheet simulations; model initialisation procedures for hierarchical flowsheets to allow better structuring of large flowsheets; and added functionality to assist in initialising pressure-driven flowsheets.

    Costas Pantelides, MD of PSE and architect of the gPROMS platform, says "ProcessBuilder is process flowsheeting for the 21st century. By leveraging the power of state-of-the-art equation-oriented technology, we are enabling companies to create new value from ?already optimised? processes, and build competitive advantage in a tight and rapidly-changing market."

    [Press Release]


    10 June 2016

    Nova Process operations incorporated within PSE

    Steve Hall appointed as Engineering Solutions Director

    PSE is pleased to announce that the activities of Nova Process, a Manchester, UK based developer of innovative engineering solutions for the process industries, are now fully integrated within PSE?s operations.

    Nova built a strong reputation for services which reduce cost and improve margins for process industry organisations, by combining extensive process knowledge and engineering experience with process modelling and data management tools. Nova brings specific expertise in process improvement, energy efficiency and heat integration technologies that complements PSE?s advanced process modelling operations.

    The new development allows Nova's experience in energy efficiency and dashboard technology to be incorporated within PSE?s products and services, further extending PSE?s capability to deliver solutions that significantly improve operating performance in Chemicals, Petrochemicals & Refining.

    Costas Pantelides, MD of PSE says "this development brings a new depth of engineering experience to PSE?s downstream businesses. In particular it will augment our offerings in the olefins plant optimisation and advanced real-time refinery monitoring and optimisation areas".

    Co-founder of Nova, Steve Hall, who becomes PSE?s Engineering Solutions Director, says "we look forward to incorporating the engineering technology and innovative solutions that had been developed by Nova within PSE?s gPROMS modelling platform, bringing powerful new capabilities to a worldwide market."

    19 May 2016

    gPROMS ProcessBuilder v1.1 is now available

    Full dynamic simulation and optimisation, new unit models and improved performance

    gPROMS ProcessBuilder v1.1 is now available for existing customers.

    The major new feature in v1.1 is the new dynamic mode within key models, including distillation columns. This makes ProcessBuilder the first integrated flowsheeting package offering true equation-oriented steady-state and dynamic simulation and optimisation within the same environment.

    In addition there are new and enhanced unit operations, including a Multi-Stream Heat Exchanger (MSHX), distributed versions of existing heat exchangers, new pipeline and Pressure Relief Valve (PRV) models and enhanced adsorption and controller models, as well as enhanced usability, speed and robustness in key areas.

    All distillation column models can now be used in dynamic mode after selecting appropriate correlations to predict pressure drops and holdups on trays. The capability has been demonstrated on large-scale refinery crude distillation systems and coupled azeotropic columns. Dynamic operation is also available in heat exchangers, pipelines, reactors, vessels and other models.

    The new Multi-Stream Heat Exchanger (MSHX) model includes a distributed mode with heat transfer and variations in fluid properties predicted along the length of each channel, and can operate in steady-state or dynamic mode. Custom correlations can be included to predict heat transfer and pressure drops for particular pieces of equipment. Similar capabilities are also found in the new distributed shell-and-tube and double-pipe heat exchanger models, and the new steady-state and dynamic pipeline, where fluid properties can vary along the length of the line. The PRV model describes the behaviour of a pressure relief valve/pressure safety valve for sizing for either a discharge coefficient or a discharge area.

    ProcessBuilder?s custom modelling option now comes supplied with a set of 'starting point' templates and examples to simplify the addition of custom unit operation models. This is particularly useful for users creating corporate libraries to be used in flowsheets in combination with standard ProcessBuilder models.

    ProcessBuilder v1.1 takes advantage of many other new features of the gPROMS platform, including the new DAEBDF solver, which offers improved robustness and significantly-increased performance for many models; sequential initialisation of hierarchical flowsheets to allow better structuring of large flowsheets; added functionality to assist in the initialisation of pressure-driven flowsheets; and further capabilities for initialising complex recycles, an area where ProcessBuilder is already strong. Automatic model pruning – the technique for removing unnecessary variables from the core solution – has been extended to remove time-invariant sub-systems for dynamic simulations, significantly accelerating dynamic flowsheet simulations and improving robustness.

    Full support for the CAPE-OPEN thermodynamic interface allows gPROMS ProcessBuilder flowsheets to call material properties from an external CAPE-OPEN compliant physical property package, and support for the gSAFT v3.1.0 physical property package provides access to new methods and components for the SAFT equation-of-state.

    22 April 2016

    Advanced Process Modelling Forum – London 20–21 April

    Applications "can increase profit by tens or hundreds of millions of Euros"

    At the 5th Advanced Process Modelling (APM) Forum in London this week, companies from across the process industries presented on topics ranging from accelerating development of the next generation of drugs to identifying hundreds of millions of Euros in operational savings in natural gas production.

    Organised and hosted by PSE, the two-day conference is a key event for process industry organisations focused on creating sustainable value through the application of high-accuracy predictive process modelling and optimisation.

    In the sessions on formulated products, aimed at the pharmaceuticals, food & beverage, consumer goods and specialty chemicals sectors, presentations from AstraZeneca, Danone, Eli Lilly, Roche, Saint-Gobain, and Solvay described how new 'digital design' techniques are improving drug product manufacture, including development of robust continuous manufacturing processes, and accelerating time-to-market for new formulations.

    A key event was the preview of PSE's forthcoming gPROMS FormulatedProducts environment for integrated design and optimisation of formulated products and their manufacturing processes. Developed in co-operation with specialists from several sectors, this allows scientists and engineers to screen formulations for end-user attributes, determine whether they can be manufactured efficiently, and then use the gPROMS platform's optimisation capabilities to optimise the whole formulation and manufacturing chain.

    In the oil & gas, chemicals, petrochemical & refining sessions, where presenters included Bharat Petroleum, BP Exploration, DSM, Primetals, SABIC, SCG Chemicals, Shell, Sulzer, Velocys and Yara International, the focus was on large-scale optimisation applications capable of improving profit by tens or hundreds of millions of Euros. These included major new developments in oilfield optimisation capable of identifying millions of dollars a day in increased production, Shell's work on region-wide optimisation of natural gas processing facilities, Bharat Petroleum's innovative work in real-time optimisation of refinery crude transition, and DSM's operational optimisation of the utility systems supplying electricity and steam to large-scale industrial sites. SABIC described how model-based analysis helped reduce the time to screen anti-coking technologies for ethylene production from years to months.

    PSE MD Costas Pantelides said, "A key focus of the conference has been the coming of age of equation-oriented (EO) process modelling tools. EO is a disruptive technology that for the first time makes it possible to optimise large-scale, complex process systems using high-fidelity models and apply techniques such as global system analysis to explore the design and operational space much more rapidly than previously possible. This is enabling companies to realise large gains in competitive advantage and dramatically accelerate innovation".

    Keynote speaker Peter Drogt of DSM, standing in for Dorus van der Linden, said that advanced process modelling is crucial technology for the organisation to accelerate innovation and quantify process decisions. A key reason for the company's move to APM is the ability to have a single unified modelling platform across the process lifecycle.

    [Press Release] [More about the APM Forum]
    [Viewand download presentations [customers and attendees only]]

    2 March 2016

    Paul Frey to lead new PSE Oil & Gas Centre of Expertise

    Propagating best practice for Pressure Relief, Flare and Blowdown

    We are pleased to announce that Paul Frey will head the company's newly established Centre of Expertise (CoE) for Pressure Relief, Flare and Blowdown.

    PSE's rigorous, high-fidelity modelling approach has brought new safety best practice to the oil & gas industry in recent years. The company is already the recognised industry-leading provider of high accuracy analysis for blowdown, pressure relief and flare system design, with a worldwide customer base of owner/operators and engineering contractors.

    The newly-established Centre of Expertise will comprise an international team of some 20 engineers providing pressure relief, flare and blowdown expertise for front-end engineering design (FEED), detailed design and asset integrity projects to owners/operators and contractors in the oil & gas, petrochemicals and refining industries. High-fidelity dynamic analysis using PSE's extensively-validated gFLARE® modelling environment will continue to be at the core of design and verification studies that help to ensure safe operation, minimise project cost and manage project risk.

    Paul has extensive experience in the oil & gas industry, most recently at AMEC Foster Wheeler where he was the Principal Consultant and technical authority in pressure relief and blowdown for Upstream, Midstream and Downstream safety. His role included activities such as technical support and auditing of projects, flare and relief verification audits and responsibility for development of relief sizing methodologies and company standards. He was also a contributor to the API 520 and 521 Pressure Relieving Standards Committee meetings.

    James Marriott, VP of PSE's Oil & Gas business, says "we are very pleased to welcome Paul to this key position. We believe that the new CoE shows PSE's commitment to bringing innovative technology and integrating advanced analysis into traditional areas of practice in a way that makes it possible to enhance safety and reduce capital cost at the same time."

    PSE is a leading provider of advanced process modelling software and services to the process industries. Its gPROMS family products, built on the gPROMS modelling and optimisation platform, are used to optimise design and operation and accelerate innovation throughout process industry sectors from oil & gas to food and pharmaceuticals.

    [Press Release]

    28 January 2016

    New £20.4m project set to transform UK pharmaceutical development and manufacturing

    gPROMS advanced process modelling used for digital design

    We are pleased to announce that PSE is the project leader for a newly-launched major collaborative project that is set to transform the UK pharmaceutical industry.

    The ADDoPT (Advanced Digital Design of Pharmaceutical Therapeutics) project is aimed at helping the pharmaceutical industry to get new, innovative medicines to market in the quickest and most cost-effective way. The collaboration will develop and implement advanced 'digital design' techniques that eliminate non-viable drug candidate formulations as early as possible, streamlining design, development and manufacturing processes.

    Digital design addresses key challenges for the industry by combining research insight and mechanistic modelling to provide links between raw materials, formulation, manufacturing processes and drug product quality. It spans all operations, processes and procedures during the development and manufacture of medicines and their in vivo application.

    ADDoPT draws on the expertise of UK technology and academic leaders in the field of digital design concepts including PSE's expertise in applying model-based techniques to explore the formulation and manufacturing decision space. The company's gPROMS® advanced process modelling platform will be applied to industrial case studies provided by the four major pharmaceutical companies (Pfizer, GSK, AstraZeneca and Bristol-Myers Squibb) within the consortium. A key objective is to achieve better design and scale-up for robust products and processes through more targeted future experimentation and better understanding of risk.

    Project Lead Sean Bermingham of Process Systems Enterprise Limited says "by building on UK excellence in process modelling, optimisation and control, we can give UK pharmaceutical development and manufacturing a genuine competitive advantage in this globally significant sector."

    [Press Release]

    24 December 2015

    gPROMS ModelBuilder v4.2 now available

    Enhancements to flowsheeting, numerical power, usability and physical property handling

    We are pleased to announce the release of gPROMS® ModelBuilder® v4.2.

    gPROMS ModelBuilder is built on the new gPROMS platform v4.2, which contains many enhancements for flowsheeting users, increases in numerical power, usability enhancements and improvements in physical property handling.

    Selected highlights of this release are:

    More detail is provided in the release notes accessible from the gPROMS ModelBuilder installation. Installers for all supported platforms are available from the customer area.

    [Download gPROMS ModelBuilder v4.2 for Windows and Linux]

    20 July 2015

    gPROMS ProcessBuilder is here!

    Next-generation flowsheeting for the chemical process industries

    Five years since the original design concept, and after three years of development and extensive beta testing by industrial users worldwide, we have just released the first official version of the gPROMS®ProcessBuilder® – arguably the first truly equation-oriented process flowsheeting tool.

    It?s been a long journey but this is a big step forward for process modelling technology. For the past 30+ years, the process modelling community has held a simple (and largely justified) consensus view: equation-oriented tools have significant advantages in terms of supporting different types of calculation (e.g. dynamic simulation; both steady-state and dynamic optimisation), efficient handling of tightly integrated processes, ease of custom modelling and so on. But (and this was a big ?but?) equation-oriented technology could not match the general robustness and reliability of steady-state sequential modular software.

    Over the last decade at PSE we have worked hard towards addressing this deficiency, with some fundamental R&D breakthroughs and many incremental improvements and enhancements in the gPROMS platform. The release of ProcessBuilder v1.0 is one outcome of these developments. We are looking forward to the feedback from all our users!

    [gPROMS ProcessBuilder home]

    24 June 2015

    gPROMS ModelBuilder v4.1 now available

    Enhancements to flowsheeting, numerical power, usability and physical property handling

    We are pleased to announce the release of gPROMS ModelBuilder® v4.1.

    gPROMS ModelBuilder is built on the new gPROMS platform v4.1, which contains many enhancements for flowsheeting users, increases in numerical power, usability enhancements and improvements in physical property handling.

    Selected highlights of this release are:

    More detail is provided in the release notes accessible from the gPROMS ModelBuilder installation, with many more enhancements described in the installed documentation.

    Installers for all supported platforms are available from the customer area of the PSE web site.

    [Download gPROMS ModelBuilder v4.1 for Windows and Linux]

    10 February 2015

    PSE's gCOAS heralds breakthrough in computational oral absorption analysis

    Formulation scientists can "bring new and better drugs to market earlier"

    PSE today announced its new gCOAS® product for computational oral absorption at the Drug Development and Formulation Summit in Düsseldorf.

    gCOAS, co-developed within the Systems-based Pharmaceutics (SbP) Alliance, is an analysis tool for a priori prediction of drug absorption in the human intestine as a function of product formulation parameters and ingestion conditions.

    It provides formulation scientists with a tool that allows them to easily and quickly screen the performance of new formulations. The ultimate objective is to design a good dosage form in terms of amount of active pharmaceutical ingredient (API), particle size distribution of the API crystals, and other relevant attributes.

    gCOAS aims to give unprecedented confidence in the accuracy of predictions of fractions absorbed using basic compound data, allowing more comprehensive early stage screening of promising candidate molecules and enabling the design of better formulations throughout the development lifecycle. These improved formulations reduce the risk to healthy volunteers and patients, as well as help reduce the number of trials, making it possible to bring new and better drugs to market earlier.

    gCOAS is a key component of PSE?s Systems-based Pharmaceutics vision, in which the formulation and manufacturing decisions are based on their effect on the efficacy of the drug. The ultimate goal of SbP is to identify the drug formulation that gives you the desired bioavailability while satisfying manufacturing constraints such as flowability and content uniformity as early as possible in the development cycle.

    [Press Release] [PDF]

    20 January 2015

    Richard Longdon appointed chairman of PSE

    AVEVA CEO joins board of rapidly-growing UK high-tech supplier to process industries

    We are pleased to announce that Richard Longdon, CEO of AVEVA Group plc (; LSE: AVV.L), the global provider of engineering software to the process industries, has been appointed as non-executive chairman of PSE. He succeeds outgoing Chairman Keith Guy, who is stepping down after more than 13 years in the position.

    Richard joined AVEVA in 1984. He was part of the management buyout team in 1994, with responsibility for worldwide sales and marketing activities at the company's London Stock Exchange listing in 1996 and was appointed Group Chief Executive in 1999. Since then, he has overseen substantial growth of the company via a number of strategic acquisitions that have given AVEVA a consistent track record of growing revenues and profits over the long term.

    Costas Pantelides, MD of PSE, says "We are immensely grateful for Keith's Guy's contribution to PSE since 2001. He has overseen the growth of the company from a small spin-out to the substantial and respected international organisation that it is today".

    He adds "Richard Longdon brings in a wealth of experience and expertise in managing and delivering growth in an international technology company, which will be invaluable in taking PSE through the next stages of its development."

    Richard Longdon says "I am very excited to be joining a company of the pedigree and reputation of PSE. The company and its products are already transforming the way the process industries around the world design and operate, and I look forward to playing my part in continuing and accelerating that success."

    PSE's gPROMS advanced process modelling technology is widely used throughout the chemicals, energy, petrochemical, food and pharmaceuticals sectors to explore the process decision space rapidly and effectively and make better, faster and safer design and operating decisions. The company's expanding global customer base of Fortune 500 process industry companies is served by operations in the UK, USA, Switzerland, Japan and Korea, and agency relationships in key developing economies.

    [Press Release] [PDF]